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B. Isler, N. von Burg, T. Kleinjung, M. Meyer, P. Stämpfli, N. Zölch & P. Neff performed magnetic resonance spectroscopy (MRS) on healthy individuals with tinnitus and no hearing loss vs. a matched control group to further elucidate the role of excitatory and inhibitory neurotransmitters in tinnitus. The novel finding of reduced Glu levels came as a surprise and is discussed in the context of a putative framework of inhibitory mechanisms related to Glu throughout the auditory pathway.